Battling for a roster spot at cornerback, second-year pro Doran Grant produced the defensive play of the game for the Bears in Thursday night's preseason-ending 28-27 loss to the Bills.

Grant intercepted an A.J. McCarron pass and returned it 33 yards for a touchdown in the first quarter, giving the Bears a 10-0 lead. The Ohio State product stepped in front of running back Travaris Cadet on the play, picked off the pass and raced down the sideline into the end zone.

"They were just throwing passes out there," Grant said. "I took a chance and got my hands on it."

Grant is listed third on the Bears' depth chart at one corner position behind Kyle Fuller and Marcus Cooper Sr., neither of whom played in Thursday night's game.

"It meant a lot," Grant said, "another chance to play, another chance to show the NFL I can play, and I had a good time."

Grant was selected by the Steelers in the fourth round of the 2015 draft and appeared in three games as a rookie. He later spent time with the Bills, Giants and Jaguars without playing in a regular-season game before joining the Bears practice squad last season.

Leaning toward Kush: Coach Matt Nagy revealed after Thursday night's game that veteran Eric Kush likely will open the season as the Bears' starting left guard.

"I'm not going to say 100 percent, but we'd probably lean toward that," Nagy said. "We'll check this tape out and get together as a staff [Friday], and we'll go through all the positions and just kind of regroup and come out of the trees as to where we are. Right now we're in the middle of everything, so let's regroup tomorrow and decide not only who we're keeping, but who are starters are going to end up being."

While Kush was held out of Thursday night's game, his chief competitor for the starting position, rookie James Daniels, played the entire contest.

"We felt it would be good to put him in there and let him get some quality reps," Nagy said. "He got a lot of reps and it will be nice to see on tape and be able to evaluate him and see."

Health report: Tight end Daniel Brown (shoulder) and outside linebacker Kasim Edebali (leg) exited Thursday night's game with injuries and did not return.

Roster notes: None of the 22 players listed as starters on the Bears depth chart played in Thursday night's preseason finale.

The starting offense Thursday night consisted of quarterback Tyler Bray, running back Taquan Mizzell, fullback Michael Burton, receivers Tanner Gentry and Bennie Fowler III, tight end Ben Braunecker, left tackle Matt McCants, left guard Daniels, center Hroniss Grasu, right guard Will Pericak and right tackle Rashaad Coward.

The starting defense was comprised of ends Bilal Nichols and Cavon Walker, nose tackle Abdullah Anderson, outside linebackers Edebali and Isaiah Irving, inside linebackers Joel Iyiegbuniwe and John Timu, cornerbacks Grant and Kevin Toliver II and safeties Nick Orr and Deiondre' Hall.

Bears who did not play included quarterbacks Mitchell Trubisky and Chase Daniel; running backs Jordan Howard, Tarik Cohen and Benny Cunningham; receivers Allen Robinson II, Taylor Gabriel, Anthony Miller and Marlon Brown; tight ends Trey Burton, Adam Shaheen and Dion Sims; offensive linemen Kush, Charles Leno Jr., Cody Whitehair, Kyle Long, Bobby Massie and Bradley Sowell; defensive ends Akiem Hicks and Jonathan Bullard; nose tackle Eddie Goldman; outside linebackers Leonard Floyd, Sam Acho and Aaron Lynch; inside linebackers Danny Trevathan, Nick Kwiatkoski, Roquan Smith, Jonathan Anderson and Josh Woods; cornerbacks Fuller, Cooper, Prince Amukamara, Bryce Callahan, Cre'Von LeBlanc and Rashard Fant; and safeties Eddie Jackson, Adrian Amos and DeAndre Houston-Carson.