Bears safety Jaquan Brisker has been downgraded from questionable to out for Sunday night's game against the Chargers.
An illness kept Brisker out of practice all week.
Additionally, defensive end Khalid Kareem has been activated from injured reserve. The four-year pro was claimed by the Bears off waivers from the Colts Aug. 30.
The Bears on Saturday also released offensive tackle Aviante Collins and safety A.J. Thomas.